Background: Musculoskeletal extrapulmonary tuberculosis is accounting for only 10-15% of all cases.Current attention has been focused on hand tuberculosis due to its increasing prevalence.This study describes an unusual case of extrapulmonary tuberculosis that manifested as a soft tissue tumor of the hand.Case Report: A 17-year-old male presented w
Abstract Background: Early administration of antibiotics in sepsis is associated with improved patient outcomes, but safe and generalizable approaches to de-escalate or discontinue antibiotics after suspected sepsis events are unknown.Methods: We used a modified Delphi approach to identify safety criteria for an opt-out protocol to guide de-escalat
A central question to biology is how pathogenic bacteria initiate acute or chronic infections.Here we describe a genetic program for cell-fate decision in the opportunistic human pathogen Staphylococcus aureus, which generates the phenotypic bifurcation of the cells into two genetically identical but different cell types during the course of an inf
Drought stress influences plant growth and development affecting some physiological processes during the growing cycle.The improvement of the drought stress resistance of the plant will allow the reduction of the water requirements of the crops, representing the new frontier for agriculture, as consequence of the ongoing climatic Colostrum changes.